Liver fat in HIV
In 61 people with HIV and fatty liver, tesamorelin cut hepatic fat fraction 37% relative to baseline over 12 months, and 35% versus 4% reached under 5% liver fat.
Lancet HIV, 2019

You must be at least 21 years of age to enter this website. 40% OFF STOREWIDE TODAY ONLY USE CODE "BIGSUNDAY"
By entering, you agree to our Terms and Disclaimer.
💸 40% OFF STOREWIDE TODAY ONLY USE CODE "BIGSUNDAY" · 💧 SPEND $49.99+ GET FREE 3ML BAC WATER + FREE 2-DAY SHIPPING! · 📦 SAME DAY SHIPPING MON / FRI BY 4PM EST
In stockA synthetic growth hormone-releasing hormone (GHRH) analog studied for its effects on growth hormone signaling and downstream metabolic pathways. Tesamorelin provides researchers with a well-characterized compound for controlled laboratory investigation. For laboratory research use only.
Size: 10MG
For laboratory research use only. Not for human or animal consumption.
Overview
Tesamorelin is a synthetic analog of growth hormone-releasing hormone that keeps all 44 amino acids of the human sequence and adds a trans-3-hexenoic acid group at the N-terminus, the cap that slows enzymatic breakdown. It stimulates the pituitary's own growth hormone release rather than replacing the hormone. It's also the rare research peptide with a regulatory record: the FDA approved it in 2010, as Egrifta, for HIV-associated lipodystrophy, so labs studying tesamorelin peptides have more human data to work from than most GHRH analogs.
That same demand drives copies. A 2026 preprint by Mendias and Awan, covering 6,441 independent test reports, found 11 tesamorelin samples that didn't contain tesamorelin at all. The subtler failure is the missing cap: the hexenoyl group adds under 100 Da to a chain of more than 5,000, so an uncapped GHRH can sit right beside the real product on a chromatogram. Mass spectrometry separates them cleanly. Titan Core's tesamorelin is made in the USA, and an independent lab checks every batch by HPLC for purity and mass spectrometry for the complete molecule, hexenoyl cap included. The report you download here carries the same LOT number as your vial. It's supplied strictly for lab research, never for use in people or animals.
Research highlights
In 61 people with HIV and fatty liver, tesamorelin cut hepatic fat fraction 37% relative to baseline over 12 months, and 35% versus 4% reached under 5% liver fat.
Lancet HIV, 2019
Paired biopsies from that trial showed tesamorelin raised oxidative-phosphorylation gene sets and lowered sets tied to inflammation and cell division.
JCI Insight, 2020
Across 92 plasma biomarkers, tesamorelin lowered 13, including CCL3, CCL4 and CD8A, and raised none.
Clinical Infectious Diseases, 2021
In 341 participants, visceral fat density rose 6.2 HU with tesamorelin versus 0.3 HU with placebo over 26 weeks.
AIDS, 2021
A 73-person phase 2 trial saw IGF-1 rise, but no significant between-group difference in neurocognitive performance at six months.
Journal of Infectious Diseases, 2025
Researchers identified 19 in vitro metabolites across four GHRH analogs, including tesamorelin, to build urine detection methods.
Drug Testing and Analysis, 2021
Specifications
Amino-acid sequence
trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂
FAQ
Online checkout is limited to 19 units per size. Fill in this quote form instead of adding to cart — we reply within 24 hours.
Related products
Research use only
A mitochondrial-derived peptide studied for its role in cellular metabolism, energy regulation, and metabolic signaling pathways. MOTS-c continues to be investigated for its unique relationship between mitochondrial signaling and cellular function. For laboratory research use only.
Research use only
A triple-receptor agonist studied for its activity at GLP-1, GIP, and glucagon receptors. Our Retatrutide is supplied as a high-purity research peptide with independent testing for identity and purity. For laboratory research use only.
Research use only
A research blend combining BPC-157 and TB-500, two peptides commonly investigated in tissue and cellular research. Each batch is independently tested to verify identity, composition, and purity. For laboratory research use only.