Research use only

TESAMORELIN

A synthetic growth hormone-releasing hormone (GHRH) analog studied for its effects on growth hormone signaling and downstream metabolic pathways. Tesamorelin provides researchers with a well-characterized compound for controlled laboratory investigation. For laboratory research use only.

99.66% purity · HPLC Lot TC-073-JZ White Lyophilized Powder

$55.99 per 10MG vial

Size: 10MG

Quantity

Download lab report (COA)
  • Third-party tested · COA for this lot
  • Ships same day when ordered before 3 PM ET
  • Free shipping on orders over $49.99
  • Questions? Contact support — 860-681-6522

For laboratory research use only. Not for human or animal consumption.

Overview

About Tesamorelin

Tesamorelin is a synthetic analog of growth hormone-releasing hormone that keeps all 44 amino acids of the human sequence and adds a trans-3-hexenoic acid group at the N-terminus, the cap that slows enzymatic breakdown. It stimulates the pituitary's own growth hormone release rather than replacing the hormone. It's also the rare research peptide with a regulatory record: the FDA approved it in 2010, as Egrifta, for HIV-associated lipodystrophy, so labs studying tesamorelin peptides have more human data to work from than most GHRH analogs.

That same demand drives copies. A 2026 preprint by Mendias and Awan, covering 6,441 independent test reports, found 11 tesamorelin samples that didn't contain tesamorelin at all. The subtler failure is the missing cap: the hexenoyl group adds under 100 Da to a chain of more than 5,000, so an uncapped GHRH can sit right beside the real product on a chromatogram. Mass spectrometry separates them cleanly. Titan Core's tesamorelin is made in the USA, and an independent lab checks every batch by HPLC for purity and mass spectrometry for the complete molecule, hexenoyl cap included. The report you download here carries the same LOT number as your vial. It's supplied strictly for lab research, never for use in people or animals.

Research highlights

What the literature reports

Liver fat in HIV

In 61 people with HIV and fatty liver, tesamorelin cut hepatic fat fraction 37% relative to baseline over 12 months, and 35% versus 4% reached under 5% liver fat.

Lancet HIV, 2019

Hepatic gene signatures

Paired biopsies from that trial showed tesamorelin raised oxidative-phosphorylation gene sets and lowered sets tied to inflammation and cell division.

JCI Insight, 2020

Immune activation markers

Across 92 plasma biomarkers, tesamorelin lowered 13, including CCL3, CCL4 and CD8A, and raised none.

Clinical Infectious Diseases, 2021

Fat quality, not just quantity

In 341 participants, visceral fat density rose 6.2 HU with tesamorelin versus 0.3 HU with placebo over 26 weeks.

AIDS, 2021

Neurocognition

A 73-person phase 2 trial saw IGF-1 rise, but no significant between-group difference in neurocognitive performance at six months.

Journal of Infectious Diseases, 2025

Detection science

Researchers identified 19 in vitro metabolites across four GHRH analogs, including tesamorelin, to build urine detection methods.

Drug Testing and Analysis, 2021

Specifications

Product details

Form
Lyophilized powder
Purity
≥99% (HPLC verified)
Molecular formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular weight
5135.9 g/mol
CAS number
218949-48-5
Presentation
10mg · 20mg
Lot
TC-073-JZ
Storage
Store lyophilized at –20°C, protected from light and moisture.

Amino-acid sequence

trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂

At a glance

  • Third-Party Tested - (COA) Available
  • Free 2-Day Shipping on Orders $49.99
  • Complete Sequence and CAS Published

FAQ

Frequently asked questions

A 44-amino-acid GHRH analog with a trans-3-hexenoyl cap. It prompts the pituitary to release growth hormone in pulses, the way native GHRH does.
Sermorelin is GHRH trimmed to its first 29 residues with no protective cap. Tesamorelin keeps all 44 and adds the cap, which makes it more resistant to enzyme breakdown.
They act on different receptors. Tesamorelin works through the GHRH receptor; ipamorelin is a short ghrelin-receptor agonist. Labs often study the two pathways side by side.
No. Ozempic's semaglutide is a GLP-1 receptor agonist. Tesamorelin acts on the growth hormone axis, a separate system.
Download the report and match its LOT to your vial. The mass result should match the molecular weight in Product Details; an uncapped or truncated chain reads lighter.
The prescription drug Egrifta is FDA approved for one HIV-related indication. Titan Core's tesamorelin is a research compound, not that medicine, and we don't advise on tesamorelin side effects or use in people.
Right here. To buy tesamorelin, register, pick a size and check out. Our tesamorelin for sale is USA-made, and weekday orders placed by 4 PM EST ship the same day.

Tesamorelin

$55.99

Add to cart

Related products

You may also like

View all products

Research use only

MOTS-C

A mitochondrial-derived peptide studied for its role in cellular metabolism, energy regulation, and metabolic signaling pathways. MOTS-c continues to be investigated for its unique relationship between mitochondrial signaling and cellular function. For laboratory research use only.

  • Third-Party Tested - (COA) Available
  • Free 2-Day Shipping on Orders $49.99
  • Unmodified Native Peptide, No Analog Swaps

Research use only

GLP-3-RT

A triple-receptor agonist studied for its activity at GLP-1, GIP, and glucagon receptors. Our Retatrutide is supplied as a high-purity research peptide with independent testing for identity and purity. For laboratory research use only.

  • Third-Party Tested - (COA) Available
  • Free 2-Day Shipping on Orders $49.99
  • Lipidated Lysine-17 Side Chain Specified

Research use only

BPC-157 + TB-500

A research blend combining BPC-157 and TB-500, two peptides commonly investigated in tissue and cellular research. Each batch is independently tested to verify identity, composition, and purity. For laboratory research use only.

  • Third-Party Tested - (COA) Available
  • Free 2-Day Shipping on Orders $49.99
  • Two Mechanisms, One Fixed Ratio