Opioid withdrawal model
In morphine-dependent rats, Selank cut the total withdrawal index by 39.6%, close to diazepam's 49.3% in the same experiment.
Bulletin of Experimental Biology and Medicine, 2022
In stockSELANK
A synthetic peptide studied primarily in neuroscience research, including investigations into neurotransmitter signaling and behavioral pathways. Selank remains a compound of interest for exploring peptide activity within the central nervous system. For laboratory research use only.
99.94% purity · HPLC Lot TC-078-JZ White Lyophilized Powder
$29.99 $29.99 per 10MG vial
Size: 10MG
- Third-party tested · COA for this lot
- Ships same day when ordered before 3 PM ET
- Free shipping on orders over $49.99
- Questions? Contact support — 860-681-6522
For laboratory research use only. Not for human or animal consumption.
Overview
About Selank
Selank started as an immune fragment. Its first four residues, Thr-Lys-Pro-Arg, are tuftsin, a tetrapeptide cut from the heavy chain of IgG antibodies. Researchers at the Institute of Molecular Genetics in Russia added a Pro-Gly-Pro tail to slow its breakdown, giving the heptapeptide TKPRPGP. That hybrid origin explains why selank peptides turn up in two very different literatures: anxiety and memory models on one side, stress, gut and immune markers on the other.
The label is where buyers get caught out. N-acetyl Selank amidate is a separate compound with an acetyl group on one end and an amide on the other, roughly 41 Da heavier than the standard chain. Forum threads trade tips on which version is "better," but for a study, the version is simply part of the method. The market doesn't make it easy: some listings never print a sequence, and one seller lists a spring batch while displaying the report from an older one. Titan Core sells the standard, unmodified heptapeptide, made in the USA. Every batch goes to an independent lab for HPLC purity and mass spectrometry, and the report carries the same LOT as your vial. Selank is sold strictly for laboratory research and isn't for human or animal use.
Research highlights
What the literature reports
Alcohol and memory
In rats given ethanol for 30 weeks, Selank prevented withdrawal-linked memory and attention deficits and blocked the ethanol-driven rise in hippocampal BDNF.
Bulletin of Experimental Biology and Medicine, 2019
Stress and the liver
Under chronic foot-shock stress, Selank reduced degenerative changes in rat hepatocytes, and higher doses restored the nucleus-to-cytoplasm ratio.
Bulletin of Experimental Biology and Medicine, 2019
Stress and the colon
In restraint-stressed rats, Selank lowered corticosterone and reduced atrophy and inflammation in the colon wall.
Bulletin of Experimental Biology and Medicine, 2020
Gut microbiota
Chronic restraint stress depleted obligate gut bacteria and favored opportunistic ones; Selank restored the balance.
Bulletin of Experimental Biology and Medicine, 2019
Identifying seized samples
Anti-doping chemists identified Selank and Semax in two unknown seized preparations and set out methods to detect them.
Drug Testing and Analysis, 2020
Specifications
Product details
- Form
- Lyophilized powder
- Purity
- ≥99% (HPLC verified)
- Molecular formula
- C₃₃H₅₇N₁₁O₉
- Molecular weight
- 751.9 g/mol
- CAS number
- 129954-34-3
- Presentation
- 10mg · 20mg
- Lot
- TC-078-JZ
- Storage
- Store lyophilized at –20°C; protect from light.
Amino-acid sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP, unmodified)
At a glance
- Third-Party Tested - (COA) Available
- Free 2-Day Shipping on Orders $49.99
- Standard TKPRPGP, Not the Acetylated Form
FAQ
Frequently asked questions
A synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, built from the immune peptide tuftsin plus a stabilizing Pro-Gly-Pro tail.
In research, mainly anxiety-like behavior, memory, stress responses and immune signaling, studied almost entirely in rodents and cell models.
Both come from the same Russian institute and share a Pro-Gly-Pro tail. Selank builds on tuftsin, an immune fragment; Semax builds on a fragment of ACTH, a stress hormone.
This is standard Selank, with no acetyl cap and no amide. The two differ in mass, so the report's mass result against Product Details shows which you hold. If its LOT doesn't match your vial, contact support before opening it.
They share a design approach and a research home, so papers frequently compare them side by side, especially in anxiety and cognition models.
It has no FDA approval. Titan Core supplies it for laboratory research only and doesn't advise on selank side effects, dosing or use in people.
Right here. To buy Selank, register, pick a size and check out. Our Selank for sale is USA-made, and weekday orders placed by 4 PM EST ship the same day.
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